Anesthetic, opioid analgesic
The substance is a partial opioid receptor antagonist (mu-receptors) and a complete kappa-receptor antagonist. During treatment, the substance is less likely to develop drug addiction, addiction and withdrawal syndrome in case of abrupt withdrawal.The product activates the antinociceptive system and disrupts the transmission of impulses that signal pain. The drug affects the higher parts of the brain.Also, Buprenex slightly inhibits conditioned reflexes, provides sleeping pills and anti coughing effect, causes euphoria, increases the tone of the vagus nerve and activates the vomiting center in the brain.
After taking medicine, pupils narrow, increases the tone of the bladder, intestines and biliary tract, intestinal peristalsis is reduced, inhibited the process of producing gastric juice, depressed breathing.
Sort out the pharmacology
At sublignal reception the maximum concentration of the substance in plasma occurs within one hour. The half-life period at intramuscular and intravenous injections is from 3 to 6 hours. The substance is well and evenly distributed over all tissues of the body, penetrating through the hematoencephalic barrier.
Metabolism https://pillintrip.com/medicine/buprenex of the substance occurs in the liver.The drug is excreted through the kidneys and with bile.An analgesic effect with sublingual use occurs within half an hour, with injection use https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=b086772e-d15a-4d13-b1a2-38bfbde1f18c – in 15-30 minutes. The effect is maintained for 6-8 hours.